The idea of isometric art in video games is normally to make a 2D game look 3D, a lot of effort goes into making this work and look right.
Our friend Unity3D helps us out a lot here, to setup an isometric game all we need to do is adjust the Main Camera settings to give us a isometric view of our scene.
Step 1: Select Main Camera from the hierarchy
Step 2: Within the Inspector and under the Transform tab change the Main Camera’s position as follows : x = -10, y = 15, z – 10
Step 3: Within the Transform tab change the Main Camera’s rotation as follows: x = 30, y = 45, z= 0
Step 4: Under the Camera tab select ‘Orthographic’ from the Projection drop-down menu, which is normally set to ‘Perspective’ as default.
Check Your Work: With a few object in your scene you will see them displayed in the Isometric style within the Game View.
Your settings should look the same as below (Unity 4.1.5):